Does Zoloft Make You Sleepy?

Published date:

2022-09-28
Score: 4.89/5 (38 votes)

Are you searching for an answer to the question: Does zoloft make you sleepy? On this page, we've collected the most accurate and complete information to ensure that you have all of the answers you need. So keep reading!

Zoloft (sertraline) can cause some insomnia or difficulty sleeping for some people, but tired or drowsiness for others. If you experience difficulty sleeping, it might help to take the medication in the morning.

You may wonder, is it normal for zoloft to make you tired? It's common to experience headaches, nausea, and fatigue during your first week on Zoloft. These side effects often get better over the first week or two.

Similarly one may ask, is it best to take zoloft in the morning or at night? Zoloft is an SSRI that treats depression and other mental health conditions. It's usually taken once a day at any time during the day. But if it makes you tired, take it in the evening. If it makes you feel more awake, take it in the morning.

Besides above, can zoloft make you sleep more? Unlike some other treatments for mental health conditions, Zoloft is not a sedative and doesn't often make you sleepier, although it can occasionally cause fatigue as a side effect. SSRIs work by increasing serotonin levels in the brain.

Likewise, how long does zoloft make you sleep? One study reports that 20% of Zoloft users experience insomnia symptoms. For some, these symptoms are short-term and improve with time while others struggle to sleep for several months to a year. If the latter describes you, you may want to consider an alternative medication.


Is 50mg of Zoloft a lot?

The maximum dose of Zoloft is 200 mg per day (which can be taken as two 100 mg tablets). Most studies suggest that the most effective dose of Zoloft is 50 mg per day. This dose is proven to be the most effective and tolerable dose for most patients.

How do I stop sertraline tiredness?

If sertraline makes you feel tired or weak, stop what you're doing and sit or lie down until you feel better. Do not drive, ride a bike or use tools or machinery if you're feeling tired. It's best not to drink alcohol as it will make you feel worse.

How do I know if Zoloft is working?

Sleep, energy, or appetite may show some improvement within the first 1-2 weeks. Improvement in these physical symptoms can be an important early signal that the medication is working. Depressed mood and lack of interest in activities may need up to 6-8 weeks to fully improve.

What should you not take with Zoloft?

Do not use sertraline with buspirone (Buspar®), fentanyl (Abstral®, Duragesic®), linezolid (Zyvox®), lithium (Eskalith®, Lithobid®), methylene blue injection, tryptophan, St John's wort, or some pain or migraine medicines (eg, rizatriptan, sumatriptan, tramadol, Frova®, Imitrex®, Maxalt®, Relpax®, Ultram®, Zomig®).

Is Zoloft similar to Xanax?

Is Zoloft similar to Xanax? Zoloft and Xanax may have similar effects on mental health conditions and similar side effects, but they are different drugs. Zoloft is meant to be taken long-term, whereas Xanax is a short-term medication. Xanax is a controlled substance and can be habit-forming.

What to expect when you start taking Zoloft?

The most common side effects to expect within the first week of starting the medication are:

  • Headache.
  • Nausea.
  • Diarrhea.
  • Dry mouth.
  • Increased sweating.
  • Feeling nervous.
  • Restlessness.
  • Fatigue or drowsiness.

Does Zoloft cause weight loss?

Weight loss is a common side effect of Zoloft, affecting children and adolescents more frequently than adults, who need close monitoring when taking this drug. According to eMedTV, 7 percent of children taking Zoloft experienced weight loss of greater than 7 percent of their body weight.

Does Zoloft cause weight gain?

For some people who take an SSRI such as Prozac (fluoxetine) or Zoloft (sertraline), one of these possible side effects is weight gain. Research suggests that the amount of weight typically gained while on an SSRI is modest.

Is sertraline sedating or activating?

Some clinicians may not be aware of the possible sedating effects of sertraline and usually dismiss the concern of sedation to a symptom of depression such as fatigue or lack of energy, untreated sleep apnea, or an adverse effect from another medication.

What does Zoloft do to the brain?

SSRIs treat depression by increasing levels of serotonin in the brain. Serotonin is one of the chemical messengers (neurotransmitters) that carry signals between brain nerve cells (neurons). SSRIs block the reabsorption (reuptake) of serotonin into neurons.

Does Zoloft help with anxiety?

Aside from its ability to improve the symptoms of depression, studies have shown that Zoloft significantly reduces¹ anxiety symptoms. Importantly, this research also showed that Zoloft is still an effective treatment for depression and anxiety regardless of any other psychiatric conditions.

How long until Zoloft side effects go away?

Taking Zoloft may make you feel uncomfortable or weird at first as your body starts to process the medication. After a week or two these side effects will go away for most people as their bodies get used to the medication.

Why do SSRIs make you tired?

Take selective serotonin reuptake inhibitors (SSRIs), like sertraline (Zoloft) and paroxetine (Paxil). “Serotonin is a calming hormone,” Breus says. “When somebody is taking an SSRI, they have more serotonin in their system for longer, which can have a sedating effect,” leading to sleepiness.

How do you know if your antidepressant is too high?

If you're taking antidepressant medication and you either feel unusually elated, or you become very terse with your loved ones, feel noticeably more irritable, or have an uncharacteristic bout of rage, then it's likely that your antidepressant dose is too high.

How long does it take for increase in Zoloft to work?

It takes about one week for levels of Zoloft to build to a steady level in your body, and then about 3 to 6 more weeks for a full therapeutic effect for most uses.


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