Why Is Trazodone Not Helping Me Sleep?

Published date:

2022-09-26
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Are you searching for an answer to the question: Why is trazodone not helping me sleep? On this page, we've collected the most accurate and complete information to ensure that you have all of the answers you need. So keep reading!

Because trazodone might not work well to treat insomnia after a few weeks, check in with your doctor periodically to discuss how it's going or whether it's still working. If you have trouble getting to sleep, take it several hours before you go to bed.

You may wonder, what if trazodone doesn't work for sleep? Typically trazodone is not the first choice of treatment for insomnia. Most medical experts recommend lifestyle changes or cognitive behavioral therapy to help treat insomnia. If this does not work, your doctor may suggest traditional sleep disorder medications including Lunesta or Ambien.

Similarly one may ask, can trazodone keep you awake at night? Recap. Trazadone treats depression, but it also makes you drowsy, which may be helpful for insomnia. It works by blocking histamines in the brain that keep you awake. However, its use is not recommended by the American Academy of Sleep Medicine.

Besides above, what is better than trazodone for sleep? One study looked at trazodone vs Ambien for insomnia. Both drugs were tolerated well with few side effects. Both trazodone and Ambien helped people in the study sleep better during the first week, but only Ambien helped people sleep better the second week. The study found Ambien to be more effective than trazodone.

Likewise, how long does it take for trazodone to kick in for sleep? Patients who take the drug for a sleep disorder can experience the sedative effects within 30 minutes, depending on the type used. Patients who take the drug as an antidepressant may not notice symptom relief for one to two weeks, and it may take up to four weeks to experience the full benefits.


What is the maximum amount of trazodone you can take?

For oral dosage form (tablets): Adults—At first, 150 milligrams (mg) per day, given in divided doses. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day.

Can you build up a tolerance to trazodone?

People prescribed trazodone who abuse the drug can risk getting used to the calming feeling that taking the medication gives them. Eventually, their tolerance builds up, making the need for a higher dosage, in order to maintain the original high, more prevalent.

Is it OK to take 100mg of trazodone for sleep?

What is the common dosage of trazodone as a sleep aid? Trazodone is most often prescribed at doses between 25mg to 100mg as a sleep aid. However, studies show lower dosages of trazodone are effective and may cause less daytime sleepiness and fewer side effects because the drug is short acting.

What should you not take with trazodone?

Do not use trazodone with buspirone (Buspar®), fentanyl (Abstral®, Duragesic®), lithium (Eskalith®, Lithobid®), tryptophan, St. John's wort, or some pain or migraine medicines (eg, sumatriptan, tramadol, Frova®, Maxalt®, Relpax®, Zomig®).

Which is better for sleep trazodone or gabapentin?

Although the overall sleep of each medication group improved significantly over time, patients who received gabapentin improved significantly more than did patients who received trazodone.

Is 50 mg trazodone enough for sleep?

Trazodone Dosage for Sleep

The starting dose is usually 50 mg to 100 mg dose at bedtime. If needed, the dose can be increased to up to 200 mg at bedtime. Those with both depression and sleep problems may need a higher dose in some cases — up to 300 mg at bedtime.

Is it OK to take melatonin with trazodone?

traZODone melatonin

Using traZODone together with melatonin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.

What is the most likely side effect of trazodone?

The most common side effects of trazodone are drowsiness, nausea, dizziness, and dry mouth (Zhang, 2014). Trazodone is generally well tolerated and may be less likely than some other antidepressants to cause insomnia, sexual side effects, and anxiety (Shin, 2020).

How long does trazodone 50 mg take to work?

Trazodone can take 1 to 2 weeks to start to work, and it can be 4 to 6 weeks before you feel the full benefit. Give the medicine at least 6 weeks to work. Some people feel worse during the first few weeks of treatment before they begin to feel better.

Which is better for sleep trazodone or melatonin?

Conclusion_ This study demonstrated that both Melatonin and Trazodone improved SQ in outpatients with MDD after 8 weeks of treatment but melatonin created greater reduction in SL than trazodone after 4 weeks.

How does trazodone 50 mg make you feel?

This medication is used to treat depression. It may help to improve your mood, appetite, and energy level as well as decrease anxiety and insomnia related to depression. Trazodone works by helping to restore the balance of a certain natural chemical (serotonin) in the brain.

What is the most likely side effect of trazodone?

The most common side effects of trazodone are drowsiness, nausea, dizziness, and dry mouth (Zhang, 2014). Trazodone is generally well tolerated and may be less likely than some other antidepressants to cause insomnia, sexual side effects, and anxiety (Shin, 2020).

How long does it take for trazodone to wear off?

Official answer. After a single dose in a healthy adult, trazodone will be mostly out of your system in one to three days. For trazodone the half-life is approximately 5 to 13 hours. This means that every 5 to 13 hours, the level in your blood will drop by 50 percent.

Is 50 mg trazodone enough for sleep?

Trazodone Dosage for Sleep

The starting dose is usually 50 mg to 100 mg dose at bedtime. If needed, the dose can be increased to up to 200 mg at bedtime. Those with both depression and sleep problems may need a higher dose in some cases — up to 300 mg at bedtime.

What are the side effects of trazodone 50 mg?

Trazodone may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • nausea.
  • vomiting.
  • diarrhea.
  • constipation.
  • changes in appetite or weight.
  • weakness or tiredness.
  • nervousness.
  • dizziness or lightheadedness.


Why Is Trazodone Not Helping Me Sleep - What other sources say:

Will trazodone help me sleep? - Drugs.com?

Trazodone can help you sleep, and sleepiness is a side effect of the medication. Doctors will sometimes prescribe trazodone for insomnia, ...

Trazodone for Sleep: Everything You Need To Know - WebMD?

At low doses, trazodone helps you go to sleep and stay asleep at night without causing you to build up a tolerance or feel sleepy during the day. This is mostly ...

Considerations Before Taking Trazodone for Insomnia?

Trazadone treats depression, but it also makes you drowsy, which may be helpful for insomnia. It works by blocking histamines in the brain that ...

Trazodone for sleep: What you need to know - SingleCare?

Trazodone is not approved as a sleep aid by the Food and Drug Administration (FDA), but rather as a treatment of depression. While it has similar properties, ...

Trazodone Vs. Ambien: Uses, Side Effects, and Comparison?

... however, trazodone may not help some individuals with sleeping. Learn more about how trazodone is compared to ambien as a sleeping pill.

Side Effects Of Taking Trazodone For Sleep?

If you use trazodone to alleviate insomnia and suddenly discontinue use, you might experience symptoms like anxiety, irritability, depression ...

Trazodone for Insomnia: A Systematic Review - PMC - NCBI?

by KY Jaffer · 2017 · Cited by 97 — They found that 50mg of trazodone administered 30 minutes before bedtime was effective for sleep maintenance but that it was possibly associated ...

Trazodone for sleep: Side effects, dosages and benefits?

Doctors generally consider trazodone safe in small doses for sleep disorders, such as insomnia. But it may not be as effective as medications ...

Trazodone For Sleep: Treatment For Short-Term Insomnia?

When taken as directed, Trazodone will help you stay asleep for a full 7-9 hours of sleep. Doctors recommend taking it right at bedtime to help you fall asleep ...


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